Topic: Essays

Last updated: March 4, 2019

The Renin-Angiotensin-Aldosterone system is very important. It helps regulate the blood pressure and blood volume within our bodies. Juxtaglomerular cells are informed when blood pressure/volume falls or when there is low sodium levels. These cells are then stimulated to release a protein called Renin. Renin is an enzyme that converts Angiotensinogen to Angiotensin I.Angiotensin is an enzyme made by the liver. When there is a change to blood volume or pressure, the receptors in the Afferent arterioles are notified.

In response Renin is released, Angiotensin is converted to angiotensin I then it goes to the kidney where Angiotensin I is converted to Angiotensin II via Angiotensin Converting Enzyme. Angiotensin II then stimulates aldosterone to retain sodium and water which then leads to increase blood pressure and volume.If the Renin-Angiotensin-Aldosterone system wasn’t in place or functioning properly, then our bodies would have no mechanism to maintain homeostasis in regards to blood pressure or volume. Blood volume/pressure would fluctuate and our body would have no way to correct this without taking some type of medication.

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It would be very problematic and could result in episodes of hypertension.


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