Topic: Health & Medicine

Last updated: February 23, 2019

Oral tablets are solid dosages and it is one of the methods of administrating the drug to
achieve better patient compliance. When the tablet is placed on the tongue, the capsule
disintegrates, and salbutamol is released immediately. Oral tablets are suitable for people
suffering from dysphagia, paediatrics, geriatrics and mental illness. The drug is absorbed
from the mouth, pharynx, oesophagus as saliva passes the stomach, therefore has a good
bioavailability. Salbutamol is a ?2 adrenergic receptor. The drug is stimulated when there are
higher levels of cyclic adenosine monophosphatedan formed in the bronchial muscle cell; this
causes relaxation (KUMAR and SAHARAN, 2017). Its action starts within 15 to 20 minutes
and can last up to 4 hours. Hence, it is an efficient method to terminate attacks of asthma.
Each tablet contains 2.4 mg of Salbutamol Sulfate (, 2018). For an adult, the
effective dose is 4 mg for three to four times a day and for children, the doses should be
administered depending on the age, for example for 2 to 6 years old is 1 to 2 mg, 6 to 12
years is 2 mg and over 12 years is 2 to 4 mg (, 2018). The advantages of
oral tablet are that fast dissolving tablets enhance safety and efficacy of the drug molecules,
the tablet can be administered without water and the dosage is accurate compared to liquids
given that it has easy portability. Further benefits are in terms of patient compliance, rapid
onset of action and increase in bioavailability (Sharma et al., 2014). The disadvantage for this
is that some patients have trouble in swallowing the drug due to large size, shape and taste.


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