Oral tablets are solid dosages and it is one of the methods of administrating the drug to achieve better patient compliance. When the tablet is placed on the tongue, the capsule disintegrates, and salbutamol is released immediately. Oral tablets are suitable for people suffering from dysphagia, paediatrics, geriatrics and mental illness. The drug is absorbed from the mouth, pharynx, oesophagus as saliva passes the stomach, therefore has a good bioavailability. Salbutamol is a ?2 adrenergic receptor.
The drug is stimulated when there are higher levels of cyclic adenosine monophosphatedan formed in the bronchial muscle cell; this causes relaxation (KUMAR and SAHARAN, 2017). Its action starts within 15 to 20 minutes and can last up to 4 hours. Hence, it is an efficient method to terminate attacks of asthma. Each tablet contains 2.4 mg of Salbutamol Sulfate (Drugs.
com, 2018). For an adult, the effective dose is 4 mg for three to four times a day and for children, the doses should be administered depending on the age, for example for 2 to 6 years old is 1 to 2 mg, 6 to 12 years is 2 mg and over 12 years is 2 to 4 mg (Medicines.org.uk, 2018). The advantages of oral tablet are that fast dissolving tablets enhance safety and efficacy of the drug molecules, the tablet can be administered without water and the dosage is accurate compared to liquids given that it has easy portability. Further benefits are in terms of patient compliance, rapid onset of action and increase in bioavailability (Sharma et al., 2014).
The disadvantage for this is that some patients have trouble in swallowing the drug due to large size, shape and taste.